By Michael Nguyen
Peer Reviewed
Polypharmacy has been defined as the use of multiple unnecessary medications, the use of more medications than is clinically warranted or indicated, or the use …
Category: Pharmacology
Clinical Correlations
Should Beta Blockers be Used in Heart Failure with Preserved Ejection Fraction?
August 23, 2017
By Lauren Christene Strazzulla
Peer Reviewed
The lifetime risk for developing heart failure from age 55 on is 33% for men and 28.5% for women, and as the population ages, there is an increasing prevalence of …
The Forbidden Fruit
January 27, 2017
By Varun Narendra
Peer Reviewed
Griffith Hughes was the first to describe the grapefruit in 1750, naming it the “forbidden fruit†of Barbados for unknown reasons. Centuries later, it seems as …
Gamechanger? Can Pioglitazone Reduce Cardiovascular Events After a Stroke? An Analysis of the IRIS Trial
January 19, 2017
By Johanna Hase, MD
Peer Reviewed
Welcome to Gamechangers, a series that takes a critical look at the latest in medical literature to answer one important question: would the results …
Lies My Patients Told Me: “I Take My Medications Every Day.â€
January 15, 2016
By Rebecca Sussman
Peer Reviewed
Reviewing medical evidence has become such a habit that sometimes it feels almost impossible to think independently. I’ve always been a top-down thinker; I go with my …
From The Archives: They’re all the ‘roid rage: origins and mechanisms of corticosteroid therapy.
April 3, 2014
Please enjoy this post from the archives dated September 23, 2011
By Santosh Vardhana, MD
A 36-year-old obese male with hypertension and hyperlipidemia presents to the ER with new knee pain, swelling, and erythema. Joint aspiration reveals negatively birefringent crystals. …
An antidote on the horizon? An update on the progress toward achieving reversibility for the new oral anticoagulants
February 21, 2014
By Gabriel Schneider, MD
Peer Reviewed
The new oral anticoagulants (NOACs) are an appealing alternative to the burdensome vitamin K antagonists such as warfarin. These novel agents include direct thrombin inhibitors such …
What Physicians Should Know About MDMA (Ecstasy)
February 20, 2014
By Loren Gorcey
Peer Reviewed
With the recent resurgence of techno music and raves in the United States, the drug MDMA, known worldwide by the name “ecstasy,†has experienced a comeback. …